(3α,5β,6α)-6-ethyl-3-hydroxy-7-oxo-cholan-24-oic acid (BTC-B1) - Names and Identifiers
(3α,5β,6α)-6-ethyl-3-hydroxy-7-oxo-cholan-24-oic acid (BTC-B1) - Physico-chemical Properties
Molecular Formula | C26H42O4
|
Molar Mass | 418.62 |
Density | 1.087±0.06 g/cm3(Predicted) |
Boling Point | 561.5±25.0 °C(Predicted) |
pKa | 4.76±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
(3α,5β,6α)-6-ethyl-3-hydroxy-7-oxo-cholan-24-oic acid (BTC-B1) - Introduction
(3α,5β,6α)-BTC-B1 is an organic compound with the chemical name (3α,5β,6α)-6-Ethyl-3-hydroxy-7-keto-chole-24-acid (BTC-B1). Its nature is as follows:
-Appearance: colorless crystalline powder
-Molecular formula: C26H42O4
-Molecular weight: 418.61g/mol
The main uses of
(3α,5β,6α)-acid (BTC-B1) are:
-is a key intermediate for the synthesis of drugs for hepatitis C therapy
-Can be used as a synthetic raw material for insulin drugs
-Intermediate products in the research field are also used in the synthesis process
The preparation method of
(3α,5β,6α)-acid (BTC-B1) is generally through the following steps:
1. Reacting cholic acid with appropriate reagents, such as hydroxylation reagents, hydrogenation reagents, etc., to obtain hydroxycholic acid intermediates;
2. The cholic acid intermediate is further ketonized or esterified to obtain (3α,5β,6α)-acid (BTC-B1).
Regarding safety information,(3α,5β,6α)-BTC-B1 (acid) is relatively safe under correct handling and storage conditions. However, as with all chemicals, it should follow proper laboratory practices and precautions. Wear gloves, goggles, and laboratory tops when used, and operate in a well-ventilated environment. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help. In addition, should be stored away from fire and sparks, away from high temperature and humidity.
Last Update:2024-04-09 20:52:54